Context-dependent interpretation of the prognostic value of BRAF and KRAS mutations in colorectal cancer

BACKGROUND: The mutation status of the BRAF and KRAS genes has been proposed as prognostic biomarker in colorectal cancer. Of them, only the BRAF V600E mutation has been validated independently as prognostic for overall survival and survival after relapse, while the prognostic value of KRAS mutation...

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Bibliografski detalji
Glavni autori: Popovici, Vlad, Budinska, Eva, Bosman, Fred T, Tejpar, Sabine, Roth, Arnaud D, Delorenzi, Mauro
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849526/
https://ncbi.nlm.nih.gov/pubmed/24073892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-439
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