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Context-dependent interpretation of the prognostic value of BRAF and KRAS mutations in colorectal cancer

BACKGROUND: The mutation status of the BRAF and KRAS genes has been proposed as prognostic biomarker in colorectal cancer. Of them, only the BRAF V600E mutation has been validated independently as prognostic for overall survival and survival after relapse, while the prognostic value of KRAS mutation...

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Bibliografiske detaljer
Main Authors: Popovici, Vlad, Budinska, Eva, Bosman, Fred T, Tejpar, Sabine, Roth, Arnaud D, Delorenzi, Mauro
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849526/
https://ncbi.nlm.nih.gov/pubmed/24073892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-439
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