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Intercellular Redistribution of cAMP Underlies Selective Suppression of Cancer Cell Growth by Connexin26

Connexins (Cx), which constitute gap junction intercellular channels in vertebrates, have been shown to suppress transformed cell growth and tumorigenesis, but the mechanism(s) still remain largely speculative. Here, we define the molecular basis by which Cx26, but less frequently Cx43 or Cx32, sele...

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Autors principals: Chandrasekhar, Anjana, Kalmykov, Edward A., Polusani, Srikanth R., Mathis, Sandra A., Zucker, Shoshanna N., Nicholson, Bruce J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849486/
https://ncbi.nlm.nih.gov/pubmed/24312655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082335
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