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Intercellular Redistribution of cAMP Underlies Selective Suppression of Cancer Cell Growth by Connexin26

Connexins (Cx), which constitute gap junction intercellular channels in vertebrates, have been shown to suppress transformed cell growth and tumorigenesis, but the mechanism(s) still remain largely speculative. Here, we define the molecular basis by which Cx26, but less frequently Cx43 or Cx32, sele...

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Auteurs principaux: Chandrasekhar, Anjana, Kalmykov, Edward A., Polusani, Srikanth R., Mathis, Sandra A., Zucker, Shoshanna N., Nicholson, Bruce J.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849486/
https://ncbi.nlm.nih.gov/pubmed/24312655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082335
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