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Intercellular Redistribution of cAMP Underlies Selective Suppression of Cancer Cell Growth by Connexin26

Connexins (Cx), which constitute gap junction intercellular channels in vertebrates, have been shown to suppress transformed cell growth and tumorigenesis, but the mechanism(s) still remain largely speculative. Here, we define the molecular basis by which Cx26, but less frequently Cx43 or Cx32, sele...

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Detalhes bibliográficos
Main Authors: Chandrasekhar, Anjana, Kalmykov, Edward A., Polusani, Srikanth R., Mathis, Sandra A., Zucker, Shoshanna N., Nicholson, Bruce J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849486/
https://ncbi.nlm.nih.gov/pubmed/24312655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082335
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