Pre-Clinical Development of a Recombinant, Replication-Competent Adenovirus Serotype 4 Vector Vaccine Expressing HIV-1 Envelope 1086 Clade C

BACKGROUND: There is a well-acknowledged need for an effective AIDS vaccine that protects against HIV-1 infection or limits in vivo viral replication. The objective of these studies is to develop a replication-competent, vaccine vector based on the adenovirus serotype 4 (Ad4) virus expressing HIV-1...

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Detalhes bibliográficos
Main Authors: Alexander, Jeff, Mendy, Jason, Vang, Lo, Avanzini, Jenny B., Garduno, Fermin, Manayani, Darly J., Ishioka, Glenn, Farness, Peggy, Ping, Li-Hua, Swanstrom, Ronald, Parks, Robert, Liao, Hua-Xin, Haynes, Barton F., Montefiori, David C., LaBranche, Celia, Smith, Jonathan, Gurwith, Marc, Mayall, Tim
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849430/
https://ncbi.nlm.nih.gov/pubmed/24312658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082380
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