Pre-Clinical Evaluation of a Replication-Competent Recombinant Adenovirus Serotype 4 Vaccine Expressing Influenza H5 Hemagglutinin

BACKGROUND: Influenza virus remains a significant health and social concern in part because of newly emerging strains, such as avian H5N1 virus. We have developed a prototype H5N1 vaccine using a recombinant, replication-competent Adenovirus serotype 4 (Ad4) vector, derived from the U.S. military Ad...

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Detalhes bibliográficos
Main Authors: Alexander, Jeff, Ward, Simone, Mendy, Jason, Manayani, Darly J., Farness, Peggy, Avanzini, Jenny B., Guenther, Ben, Garduno, Fermin, Jow, Lily, Snarsky, Victoria, Ishioka, Glenn, Dong, Xin, Vang, Lo, Newman, Mark J., Mayall, Tim
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281928/
https://ncbi.nlm.nih.gov/pubmed/22363572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031177
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