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SNP ascertainment bias in population genetic analyses: Why it is important, and how to correct it

Whole genome sequencing and SNP genotyping arrays can paint strikingly different pictures of demographic history and natural selection. This is because genotyping arrays contain biased sets of pre-ascertained SNPs. In this short review, we use comparisons between high-coverage whole genome sequences...

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Hlavní autoři: Lachance, Joseph, Tishkoff, Sarah A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849385/
https://ncbi.nlm.nih.gov/pubmed/23836388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201300014
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