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Identifying Cytochrome P450 Functional Networks and Their Allosteric Regulatory Elements
Cytochrome P450 (CYP) enzymes play key roles in drug metabolism and adverse drug-drug interactions. Despite tremendous efforts in the past decades, essential questions regarding the function and activity of CYPs remain unanswered. Here, we used a combination of sequence-based co-evolutionary analysi...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3849357/ https://ncbi.nlm.nih.gov/pubmed/24312617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081980 |
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