Predictive and Prognostic Analysis of PIK3CA Mutation in Stage III Colon Cancer Intergroup Trial

BACKGROUND: Somatic mutations in PIK3CA (phosphatidylinositol-4,5-bisphosphonate 3-kinase [PI3K], catalytic subunit alpha gene) activate the PI3K-AKT signaling pathway and contribute to pathogenesis of various malignancies, including colorectal cancer. METHODS: We examined associations of PIK3CA onc...

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Bibliografiset tiedot
Päätekijät: Ogino, Shuji, Liao, Xiaoyun, Imamura, Yu, Yamauchi, Mai, McCleary, Nadine J., Ng, Kimmie, Niedzwiecki, Donna, Saltz, Leonard B., Mayer, Robert J., Whittom, Renaud, Hantel, Alexander, Benson, Al B., Mowat, Rex B., Spiegelman, Donna, Goldberg, Richard M., Bertagnolli, Monica M., Meyerhardt, Jeffrey A., Fuchs, Charles S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2013
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3848984/
https://ncbi.nlm.nih.gov/pubmed/24231454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djt298
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