Chromosome-12 Mapping of Late-Onset Alzheimer Disease among Caribbean Hispanics

Linkage to chromosome 12p for familial Alzheimer disease (AD) has been inconsistent. Using 35 markers near the centromere of chromosome 12, we investigated 79 Caribbean Hispanic families with AD. Two-point linkage analysis using affected sib pairs yielded LOD scores of 3.15 at D12S1623 and 1.43 at D...

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Main Authors: Mayeux, R., Lee, J. H., Romas, S. N., Mayo, D., Santana, V., Williamson, J., Ciappa, A., Rondon, H. Z., Estevez, P., Lantigua, R., Medrano, M., Torres, M., Stern, Y., Tycko, B., Knowles, J. A.
格式: Artigo
語言:Inglês
出版: The American Society of Human Genetics 2002
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC384892/
https://ncbi.nlm.nih.gov/pubmed/11715112
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