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Alveolar macrophages of GM-CSF knockout mice exhibit mixed M1 and M2 phenotypes
BACKGROUND: Activin A is a pleiotrophic regulatory cytokine, the ablation of which is neonatal lethal. Healthy human alveolar macrophages (AMs) constitutively express activin A, but AMs of patients with pulmonary alveolar proteinosis (PAP) are deficient in activin A. PAP is an autoimmune lung diseas...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3848434/ https://ncbi.nlm.nih.gov/pubmed/24044676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-14-41 |
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