Alveolar macrophages of GM-CSF knockout mice exhibit mixed M1 and M2 phenotypes

BACKGROUND: Activin A is a pleiotrophic regulatory cytokine, the ablation of which is neonatal lethal. Healthy human alveolar macrophages (AMs) constitutively express activin A, but AMs of patients with pulmonary alveolar proteinosis (PAP) are deficient in activin A. PAP is an autoimmune lung diseas...

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Bibliografiska uppgifter
Huvudupphovsmän: Dalrymple, Heidi, Barna, Barbara P, Malur, Anagha, Malur, Achut G, Kavuru, Mani S, Thomassen, Mary Jane
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3848434/
https://ncbi.nlm.nih.gov/pubmed/24044676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-14-41
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