Peroxisome proliferator-activated receptor γ is required in mature white and brown adipocytes for their survival in the mouse

The peroxisome proliferator-activated receptor γ (PPARγ) mediates the activity of the insulin-sensitizing thiazolidinediones and plays an important role in adipocyte differentiation and fat accretion. The analysis of PPARγ functions in mature adipocytes is precluded by lethality of PPARγ(–/–) fetuse...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Imai, Takeshi, Takakuwa, Reiko, Marchand, Sandra, Dentz, Emilie, Bornert, Jean-Marc, Messaddeq, Nadia, Wendling, Olivia, Mark, Manuel, Desvergne, Béatrice, Wahli, Walter, Chambon, Pierre, Metzger, Daniel
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2004
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC384783/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15070754/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0400356101
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