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3′ UTR-isoform choice has limited influence on the stability and translational efficiency of most mRNAs in mouse fibroblasts

Variation in protein output across the genome is controlled at several levels, but the relative contributions of different regulatory mechanisms remain poorly understood. Here, we obtained global measurements of decay and translation rates for mRNAs with alternative 3′ untranslated regions (3′ UTRs)...

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Detalhes bibliográficos
Main Authors: Spies, Noah, Burge, Christopher B., Bartel, David P.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3847777/
https://ncbi.nlm.nih.gov/pubmed/24072873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.156919.113
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