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DNA methylation profiling in human B cells reveals immune regulatory elements and epigenetic plasticity at Alu elements during B-cell activation

Memory is a hallmark of adaptive immunity, wherein lymphocytes mount a superior response to a previously encountered antigen. It has been speculated that epigenetic alterations in memory lymphocytes contribute to their functional distinction from their naive counterparts. However, the nature and ext...

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Bibliografski detalji
Glavni autori: Lai, Anne Y., Mav, Deepak, Shah, Ruchir, Grimm, Sara A., Phadke, Dhiral, Hatzi, Katerina, Melnick, Ari, Geigerman, Cissy, Sobol, Steve E., Jaye, David L., Wade, Paul A.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3847773/
https://ncbi.nlm.nih.gov/pubmed/24013550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.155473.113
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