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DNA methylation prevents CTCF-mediated silencing of the oncogene BCL6 in B cell lymphomas
Aberrant DNA methylation commonly occurs in cancer cells where it has been implicated in the epigenetic silencing of tumor suppressor genes. Additional roles for DNA methylation, such as transcriptional activation, have been predicted but have yet to be clearly demonstrated. The BCL6 oncogene is imp...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2931164/ https://ncbi.nlm.nih.gov/pubmed/20733034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100204 |
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