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Regulation of cyclin-dependent kinase activity during mitotic exit and maintenance of genome stability by p21, p27, and p107

To study the regulation of cyclin-dependent kinase (CDK) activity during mitotic exit in mammalian cells, we constructed murine cell lines that constitutively express a stabilized mutant of cyclin A (cyclin A47). Even though cyclin A47 was expressed throughout mitosis and in G(1) cells, its associat...

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Detalhes bibliográficos
Main Authors: Chibazakura, Taku, McGrew, Seth G., Cooper, Jonathan A., Yoshikawa, Hirofumi, Roberts, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC384770/
https://ncbi.nlm.nih.gov/pubmed/15070741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400655101
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