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Analysis of the mitotic exit control system using locked levels of stable mitotic cyclin
Cyclin-dependent kinase (Cdk) both promotes mitotic entry (spindle assembly and anaphase) and inhibits mitotic exit (spindle disassembly and cytokinesis), leading to an elegant quantitative hypothesis that a single cyclin oscillation can function as a ratchet to order these events. This ratchet is a...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2795472/ https://ncbi.nlm.nih.gov/pubmed/19920813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2009.78 |
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