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Cyclin A Promotes S-Phase Entry via Interaction with the Replication Licensing Factor Mcm7
Cyclin A is known to promote S-phase entry in mammals, but its critical targets in this process have not been defined. We derived a novel human cyclin A mutant (CycA-C1), which can activate cyclin-dependent kinase but cannot promote S-phase entry, and isolated replication licensing factor Mcm7 as a...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3019979/ https://ncbi.nlm.nih.gov/pubmed/21078875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00630-10 |
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