Exploring amyloid formation by a de novo design

Protein deposition as amyloid fibrils underlies many debilitating human disorders. The complexity and size of disease-related polypeptides, however, often hinders a detailed rational approach to study effects that contribute to the process of amyloid formation. We report here a simplified peptide se...

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Detalhes bibliográficos
Main Authors: Kammerer, Richard A., Kostrewa, Dirk, Zurdo, Jesús, Detken, Andreas, García-Echeverría, Carlos, Green, Janelle D., Müller, Shirley A., Meier, Beat H., Winkler, Fritz K., Dobson, Christopher M., Steinmetz, Michel O.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC384765/
https://ncbi.nlm.nih.gov/pubmed/15070736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0306786101
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