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Gene disruption confirms a critical role for the cysteine protease falcipain-2 in hemoglobin hydrolysis by Plasmodium falciparum

Erythrocytic malaria parasites degrade hemoglobin in an acidic food vacuole to acquire free amino acids and maintain parasite homeostasis. Hemoglobin hydrolysis appears to be a cooperative process requiring cysteine proteases (falcipains) and aspartic proteases (plasmepsins), but the specific roles...

詳細記述

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書誌詳細
主要な著者: Sijwali, Puran S., Rosenthal, Philip J.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC384756/
https://ncbi.nlm.nih.gov/pubmed/15070727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307720101
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