Innate immunity activation involved in unprotected porcine auto-transplant kidneys preserved by naked caspase-3 siRNA

BACKGROUND: The naked caspase-3 small interfering RNA (siRNA) infused into the renal artery during cold preservation was effective, but did not protect auto-transplant porcine kidneys with increased inflammation and apoptosis in our previous study. The mechanisms involved, in particular, whether siR...

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Detalhes bibliográficos
Main Authors: Yang, Cheng, Li, Long, Xue, Yinjia, Zhao, Zitong, Zhao, Tian, Jia, Yichen, Rong, Ruiming, Xu, Ming, Nicholson, Michael L, Zhu, Tongyu, Yang, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3847504/
https://ncbi.nlm.nih.gov/pubmed/24034868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-11-210
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