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Activation of Stat 5b in erythroid progenitors correlates with the ability of ErbB to induce sustained cell proliferation.

Self renewal of normal erythroid progenitors is induced by the receptor tyrosine kinase c-ErbB, whereas other receptors (c-Kit/Epo-R) regulate erythroid differentiation. To address possible mechanisms that could explain this selective activity of c-ErbB, we analyzed the ability of these receptors to...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Mellitzer, G, Wessely, O, Decker, T, Meinke, A, Hayman, M J, Beug, H
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38474/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8790376/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.18.9600
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