Activation of Stat 5b in erythroid progenitors correlates with the ability of ErbB to induce sustained cell proliferation.

Self renewal of normal erythroid progenitors is induced by the receptor tyrosine kinase c-ErbB, whereas other receptors (c-Kit/Epo-R) regulate erythroid differentiation. To address possible mechanisms that could explain this selective activity of c-ErbB, we analyzed the ability of these receptors to...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Mellitzer, G, Wessely, O, Decker, T, Meinke, A, Hayman, M J, Beug, H
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38474/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8790376/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.18.9600
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