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Activation of Stat 5b in erythroid progenitors correlates with the ability of ErbB to induce sustained cell proliferation.

Self renewal of normal erythroid progenitors is induced by the receptor tyrosine kinase c-ErbB, whereas other receptors (c-Kit/Epo-R) regulate erythroid differentiation. To address possible mechanisms that could explain this selective activity of c-ErbB, we analyzed the ability of these receptors to...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphov: Mellitzer, G, Wessely, O, Decker, T, Meinke, A, Hayman, M J, Beug, H
Materialtyp: Artigo
Språk:Inglês
Utgiven: National Academy of Sciences 1996
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38474/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8790376/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.18.9600
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