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Insulin-like growth factor-binding protein 5 (Igfbp5) compromises survival, growth, muscle development, and fertility in mice

The insulin-like growth factors (IGFs) are essential for development; bioavailable IGF is tightly regulated by six related IGF-binding proteins (IGFBPs). Igfbp5 is the most conserved and is developmentally up-regulated in key lineages and pathologies; in vitro studies suggest that IGFBP-5 functions...

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Detalhes bibliográficos
Main Authors: Salih, Dervis A. M., Tripathi, Gyanendra, Holding, Cathy, Szestak, Tadge A. M., Gonzalez, M. Ivelisse, Carter, Emma J., Cobb, Laura J., Eisemann, Joan E., Pell, Jennifer M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC384738/
https://ncbi.nlm.nih.gov/pubmed/15010534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400230101
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