Insulin-Like Growth Factor-Binding Protein-5 Induces a Gender-Related Decrease in Bone Mineral Density in Transgenic Mice

IGF-binding protein-5 (IGFBP-5) is abundant in serum and bone during normal skeletal development, but levels decrease in osteoporosis. Studies have shown that IGFBP-5 stimulates markers of bone formation by potentiating IGF actions and by IGF-independent actions. To test the hypothesis that IGFBP-5...

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Detalhes bibliográficos
Main Authors: Salih, Dervis A. M., Mohan, Subburaman, Kasukawa, Yuji, Tripathi, Gyanendra, Lovett, Fiona A., Anderson, Neil F., Carter, Emma J., Wergedal, Jon E., Baylink, David J., Pell, Jennifer M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897135/
https://ncbi.nlm.nih.gov/pubmed/15550514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2004-0816
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