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Role of the p63-FoxN1 regulatory axis in thymic epithelial cell homeostasis during aging

The p63 gene regulates thymic epithelial cell (TEC) proliferation, whereas FoxN1 regulates their differentiation. However, their collaborative role in the regulation of TEC homeostasis during thymic aging is largely unknown. In murine models, the proportion of TAp63(+), but not ΔNp63(+), TECs was in...

詳細記述

保存先:
書誌詳細
主要な著者: Burnley, P, Rahman, M, Wang, H, Zhang, Z, Sun, X, Zhuge, Q, Su, D-M
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3847336/
https://ncbi.nlm.nih.gov/pubmed/24263106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.460
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