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Postnatal Tissue-specific Disruption of Transcription Factor FoxN1 Triggers Acute Thymic Atrophy

The transcription factor FoxN1 is essential for differentiation of thymic epithelial cell (TEC) progenitors during thymic organogenesis. However, limited information is available on the postnatal contribution of FoxN1 to thymic maintenance. To address this question, we generated a loxP-floxed FoxN1...

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Detalhes bibliográficos
Main Authors: Cheng, Lili, Guo, Jianfei, Sun, Liguang, Fu, Jian, Barnes, Peter F., Metzger, Daniel, Chambon, Pierre, Oshima, Robert G., Amagai, Takashi, Su, Dong-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820809/
https://ncbi.nlm.nih.gov/pubmed/19955175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.072124
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