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Dual role of the p38 MAPK/cPLA(2) pathway in the regulation of platelet apoptosis induced by ABT-737 and strong platelet agonists

p38 Mitogen-activated protein (MAP) kinase is involved in the apoptosis of nucleated cells. Although platelets are anucleated cells, apoptotic proteins have been shown to regulate platelet lifespan. However, the involvement of p38 MAP kinase in platelet apoptosis is not yet clearly defined. Therefor...

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Bibliografiske detaljer
Main Authors: Rukoyatkina, N, Mindukshev, I, Walter, U, Gambaryan, S
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3847335/
https://ncbi.nlm.nih.gov/pubmed/24263105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.459
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