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ARC synergizes with ABT-737 to induce apoptosis in human cancer cells

Previously, we reported that the nucleoside analog/transcriptional inhibitor ARC was able to induce p53-independent apoptosis in multiple cancer cell lines of different origin. This occurred at least in part by the suppression of short-lived, pro-survival member of the Bcl-2 family, Mcl-1. In contra...

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Detalhes bibliográficos
Main Authors: Bhat, Uppoor G., Pandit, Bulbul, Gartel, Andrei L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902270/
https://ncbi.nlm.nih.gov/pubmed/20515947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-09-0919
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