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Thiazole Antibiotic Thiostrepton Synergize with Bortezomib to Induce Apoptosis in Cancer Cells

Thiazole antibiotic, thiostrepton was recently identified as proteasome inhibitor. We investigated the therapeutic potential of the combination of thiostrepton and proteasome inhibitor bortezomib (Velcade) on various human tumor cell lines. Combination of sub-lethal concentrations of thiostrepton an...

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Hlavní autoři: Pandit, Bulbul, Gartel, Andrei L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041825/
https://ncbi.nlm.nih.gov/pubmed/21365012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017110
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