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Proteasome Inhibitors Induce p53-Independent Apoptosis in Human Cancer Cells
Proteasome inhibitors are used against human cancer, but their mechanisms of action are not entirely understood. For example, the role of the tumor suppressor p53 is controversial. We reevaluated the role of p53 in proteasome inhibitor-induced apoptosis by using isogenic human cancer cell lines with...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3069903/ https://ncbi.nlm.nih.gov/pubmed/21224072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.11.010 |
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