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Proteasome Inhibitors Induce p53-Independent Apoptosis in Human Cancer Cells

Proteasome inhibitors are used against human cancer, but their mechanisms of action are not entirely understood. For example, the role of the tumor suppressor p53 is controversial. We reevaluated the role of p53 in proteasome inhibitor-induced apoptosis by using isogenic human cancer cell lines with...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Pandit, Bulbul, Gartel, Andrei L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Investigative Pathology 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069903/
https://ncbi.nlm.nih.gov/pubmed/21224072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.11.010
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