Proliferation inhibition and apoptosis induction of imatinib-resistant chronic myeloid leukemia cells via PPP2R5C down-regulation

Despite the success of imatinib and other tyrosine kinase inhibitors (TKIs), chronic myeloid leukemia (CML) remains largely incurable, and a number of CML patients die due to Abl mutation-related drug resistance and blast crisis. The aim of this study was to evaluate proliferation inhibition and apo...

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Main Authors: Shen, Qi, Liu, Sichu, Chen, Yu, Yang, Lijian, Chen, Shaohua, Wu, Xiuli, Li, Bo, Lu, Yuhong, Zhu, Kanger, Li, Yangqiu
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3847136/
https://ncbi.nlm.nih.gov/pubmed/24004697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-6-64
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