Alteration of gene expression profile following PPP2R5C knockdown may be associated with proliferation suppression and increased apoptosis of K562 cells

We reported that knockdown of PPP2R5C by siRNA led to proliferation inhibition and apoptosis induction in K562 cells. In this study, we further characterized the gene expression profiles after PPP2R5C suppression by microarray analysis. Genes which participate in the MAPK, PI3K/AKT, and JAK/STAT pat...

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Detalles Bibliográficos
Publicado en:J Hematol Oncol
Main Authors: Liu, Sichu, Shen, Qi, Chen, Yu, Zeng, Chengwu, Cao, Changshu, Yang, Lijian, Chen, Shaohua, Wu, Xiuli, Li, Bo, Li, Yangqiu
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2015
Assuntos:
Letter to the Editor
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414434/
https://ncbi.nlm.nih.gov/pubmed/25888193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-015-0125-5
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