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Knockdown of ZNF268, which Is Transcriptionally Downregulated by GATA-1, Promotes Proliferation of K562 Cells

The human ZNF268 gene encodes a typical KRAB-C2H2 zinc finger protein that may participate in hematopoiesis and leukemogenesis. A recent microarray study revealed that ZNF268 expression continuously decreases during erythropoiesis. However, the molecular mechanisms underlying regulation of ZNF268 du...

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Autors principals: Zeng, Yan, Wang, Wei, Ma, Jian, Wang, Xianguo, Guo, Mingxiong, Li, Wenxin
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250450/
https://ncbi.nlm.nih.gov/pubmed/22235304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029518
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