Impressive thrombocytosis evolving in a patient with a BCR-ABL positive CML in major molecular response during dasatinib treatment unmasks an additional JAK2V617F

We present a case of a 42-year old female with the rare diagnosis of a myeloproliferative syndrome harboring both a BCR-ABL transclocation and a JAK2V617F mutation. Initially diagnosed with a CML, the patient underwent treatment with imatinib followed by dasatinib. Despite a major molecular response...

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Autores principales: Pastore, Friederike, Schneider, Stephanie, Christ, Oliver, Hiddemann, Wolfgang, Spiekermann, Karsten
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2013
Materias:
Case Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3847069/
https://ncbi.nlm.nih.gov/pubmed/24007855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2162-3619-2-24
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