Inhibition of Mitochondrial Complex III Blocks Neuronal Differentiation and Maintains Embryonic Stem Cell Pluripotency

The mitochondrion is emerging as a key organelle in stem cell biology, acting as a regulator of stem cell pluripotency and differentiation. In this study we sought to understand the effect of mitochondrial complex III inhibition during neuronal differentiation of mouse embryonic stem cells. When exp...

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Main Authors: Pereira, Sandro L., Grãos, Mário, Rodrigues, Ana Sofia, Anjo, Sandra I., Carvalho, Rui A., Oliveira, Paulo J., Arenas, Ernest, Ramalho-Santos, João
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3847032/
https://ncbi.nlm.nih.gov/pubmed/24312632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082095
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