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A Mathematical Model of the Enhanced Permeability and Retention Effect for Liposome Transport in Solid Tumors

The discovery of the enhanced permeability and retention (EPR) effect has resulted in the development of nanomedicines, including liposome-based formulations of drugs, as cancer therapies. The use of liposomes has resulted in substantial increases in accumulation of drugs in solid tumors; yet, signi...

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Détails bibliographiques
Auteurs principaux: Stapleton, Shawn, Milosevic, Michael, Allen, Christine, Zheng, Jinzi, Dunne, Michael, Yeung, Ivan, Jaffray, David A.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3846845/
https://ncbi.nlm.nih.gov/pubmed/24312530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081157
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