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A Mathematical Model of the Enhanced Permeability and Retention Effect for Liposome Transport in Solid Tumors

The discovery of the enhanced permeability and retention (EPR) effect has resulted in the development of nanomedicines, including liposome-based formulations of drugs, as cancer therapies. The use of liposomes has resulted in substantial increases in accumulation of drugs in solid tumors; yet, signi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Stapleton, Shawn, Milosevic, Michael, Allen, Christine, Zheng, Jinzi, Dunne, Michael, Yeung, Ivan, Jaffray, David A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3846845/
https://ncbi.nlm.nih.gov/pubmed/24312530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081157
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