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A Mathematical Model of the Enhanced Permeability and Retention Effect for Liposome Transport in Solid Tumors

The discovery of the enhanced permeability and retention (EPR) effect has resulted in the development of nanomedicines, including liposome-based formulations of drugs, as cancer therapies. The use of liposomes has resulted in substantial increases in accumulation of drugs in solid tumors; yet, signi...

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Detalhes bibliográficos
Main Authors: Stapleton, Shawn, Milosevic, Michael, Allen, Christine, Zheng, Jinzi, Dunne, Michael, Yeung, Ivan, Jaffray, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3846845/
https://ncbi.nlm.nih.gov/pubmed/24312530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081157
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