Targeted Nanomedicine for Suppression of CD44 and Simultaneous Cell Death Induction in Ovarian Cancer: an Optimal Delivery of siRNA and Anticancer Drug

PURPOSE: The proposed project is aimed at enhancing the efficiency of epithelial ovarian cancer treatment and reducing adverse side effects of chemotherapy using nanotechnology. Overexpression of the CD44 membrane receptor results in tumor initiation, growth, tumor stem cells specific behavior, deve...

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Bibliographic Details
Main Authors: Shah, Vatsal, Taratula, Oleh, Garbuzenko, Olga B., Taratula, Olena R., Rodriguez-Rodriguez, Lorna, Minko, Tamara
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3846837/
https://ncbi.nlm.nih.gov/pubmed/24036854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-1536
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