Evaluation of the Stability, Bioavailability, and Hypersensitivity of the Omega-3 Derived Anti-Leukemic Prostaglandin: Δ(12)-Prostaglandin J(3)

Previous studies have demonstrated the ability of an eicosapentaenoic acid (EPA)-derived endogenous cyclopentenone prostaglandin (CyPG) metabolite, Δ(12)-PGJ(3), to selectively target leukemic stem cells, but not the normal hematopoietic stems cells, in in vitro and in vivo models of chronic myeloge...

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Bibliografiske detaljer
Main Authors: Kudva, Avinash K., Kaushal, Naveen, Mohinta, Sonia, Kennett, Mary J., August, Avery, Paulson, Robert F., Prabhu, K. Sandeep
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3846793/
https://ncbi.nlm.nih.gov/pubmed/24312486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080622
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