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BAP1 deficiency causes loss of melanocytic cell identity in uveal melanoma

BACKGROUND: Uveal melanoma is a highly aggressive cancer with a strong propensity for metastasis, yet little is known about the biological mechanisms underlying this metastatic potential. We recently showed that most metastasizing uveal melanomas, which exhibit a class 2 gene expression profile, con...

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Autores principales: Matatall, Katie A, Agapova, Olga A, Onken, Michael D, Worley, Lori A, Bowcock, Anne M, Harbour, J William
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3846494/
https://ncbi.nlm.nih.gov/pubmed/23915344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-371
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