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Frequent Mutation of BAP1 in Metastasizing Uveal Melanomas
Metastasis is a defining feature of malignant tumors and is the most common cause of cancer-related death, yet the genetics of metastasis are poorly understood. We used massively parallel exome sequencing coupled with Sanger re-sequencing to search for metastasis-related mutations in highly metastat...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3087380/ https://ncbi.nlm.nih.gov/pubmed/21051595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1194472 |
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