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Frequent Mutation of BAP1 in Metastasizing Uveal Melanomas

Metastasis is a defining feature of malignant tumors and is the most common cause of cancer-related death, yet the genetics of metastasis are poorly understood. We used massively parallel exome sequencing coupled with Sanger re-sequencing to search for metastasis-related mutations in highly metastat...

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Main Authors: Harbour, J. William, Onken, Michael D., Roberson, Elisha D.O., Duan, Shenghui, Cao, Li, Worley, Lori A., Council, M. Laurin, Matatall, Katie A., Helms, Cynthia, Bowcock, Anne M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087380/
https://ncbi.nlm.nih.gov/pubmed/21051595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1194472
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