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Association between gene expression classification, proliferation and metastasis in uveal melanoma

PURPOSE: Uveal melanomas cluster into two molecular groups based on their gene expression profile. Tumors with the class 1 signature rarely metastasize, whereas those with the class 2 signature have a very high rate of metastasis. However, the biological basis for this metastatic propensity of class...

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Hlavní autoři: Onken, Michael D., Worley, Lori A., Harbour, J. William
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230327/
https://ncbi.nlm.nih.gov/pubmed/20795869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/02713683.2010.493265
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