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Identification of a single amino acid in GluN1 that is critical for glycine-primed internalization of NMDA receptors
BACKGROUND: NMDA receptors are ligand-gated ion channels with essential roles in glutamatergic synaptic transmission and plasticity in the CNS. As co-receptors for glutamate and glycine, gating of the NMDA receptor/channel pore requires agonist binding to the glycine sites, as well as to the glutama...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3846451/ https://ncbi.nlm.nih.gov/pubmed/23941530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-6-36 |
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