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Mechanism and Enantioselectivity in Palladium-Catalyzed Conjugate Addition of Arylboronic Acids to β-Substituted Cyclic Enones: Insights from Computation and Experiment

Enantioselective conjugate additions of arylboronic acids to β-substituted cyclic enones have been reported previously from our laboratories. Air and moisture tolerant conditions were achieved with a catalyst derived in situ from palladium(II) trifluoroacetate and the chiral ligand (S)-t-BuPyOx. We...

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מידע ביבליוגרפי
Main Authors: Holder, Jeffrey C., Zou, Lufeng, Marziale, Alexander N., Liu, Peng, Lan, Yu, Gatti, Michele, Kikushima, Kotaro, Houk, K. N., Stoltz, Brian M.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3846424/
https://ncbi.nlm.nih.gov/pubmed/24028424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja401713g
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