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Palladium-Catalyzed Asymmetric Conjugate Addition of Arylboronic Acids to 5- 6- and 7-Membered β-substituted Cyclic Enones: Enantioselective Construction of All-Carbon Quaternary Stereocenters

The first enantioselective Pd-catalyzed construction of all-carbon quaternary stereocenters via 1,4-addition of arylboronic acids to β-substituted cyclic enones is reported. Reaction of a wide range of arylboronic acids and cyclic enones using a catalyst prepared from Pd(OCOCF(3))(2) and a chiral py...

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Bibliografski detalji
Glavni autori: Kikushima, Kotaro, Holder, Jeffrey C., Gatti, Michele, Stoltz, Brian M.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087848/
https://ncbi.nlm.nih.gov/pubmed/21495647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja200664x
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